منابع مشابه
Idarucizumab for Dabigatran Reversal.
BACKGROUND Specific reversal agents for non-vitamin K antagonist oral anticoagulants are lacking. Idarucizumab, an antibody fragment, was developed to reverse the anticoagulant effects of dabigatran. METHODS We undertook this prospective cohort study to determine the safety of 5 g of intravenous idarucizumab and its capacity to reverse the anticoagulant effects of dabigatran in patients who h...
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INTRODUCTION Potent and consistent P2Y12 receptor inhibition is associated with reduced risk of atherothrombotic events in patients presenting with acute coronary syndromes (ACS), but with inevitable increased risk of bleeding as demonstrated in TRITON and PLATO trials – a finding that is especially pertinent to the treatment of medically managed NSTE ACS patients, who typical have a greater bu...
متن کاملAnaphylaxis after Idarucizumab Infusion
Dear Editor, Dabigatran etexilate is commonly used for the prevention of stroke in patients with nonvalvular atrial fibrillation, and is as effective as and safer than warfarin.1 However, there is no reversal agent despite serious outcomes of bleeding complication,2 with hemodialysis being the only reliable option. Idarucizumab has recently been developed as a genuine reversal agent of dabigatr...
متن کاملIdarucizumab for Dabigatran Reversal - Full Cohort Analysis.
BACKGROUND Idarucizumab, a monoclonal antibody fragment, was developed to reverse the anticoagulant effect of dabigatran. METHODS We performed a multicenter, prospective, open-label study to determine whether 5 g of intravenous idarucizumab would be able to reverse the anticoagulant effect of dabigatran in patients who had uncontrolled bleeding (group A) or were about to undergo an urgent pro...
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M early psychological interventions are no better at reducing posttraumatic stress disorder symptoms than no intervention at all and might even increase symptoms in some individuals, a review of 11 randomized controlled studies shows. “There was no evidence that a multiple session intervention aimed at everyone following a traumatic event was effective. There was a trend that just failed to rea...
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ژورنال
عنوان ژورنال: Deutsches Aerzteblatt Online
سال: 2016
ISSN: 1866-0452
DOI: 10.3238/arztebl.2016.0541a